論文
海外誌
- Okada A, Aoki H, Onozato D, Kato T, Hashita T, Takase H, Sugino T, Unno R, Taguchi K, Hamamoto S, Ando R, Mizuno K, Tozawa K, Matsunaga T, Kohri K, Yasui T.
Active Phagocytosis and diachronic processing of calcium oxalate monohydrate crystals in an in vitro macrophage model.
Kidney Blood Press Res., 44(5);1014-25:2019.
- Aoki H, Yamashita M, Hashita T, Nakayama T, Yagi M, Iwao T, Matsunaga T.
Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.
Biochem. Biophys. Res Commun., 515;672-8:2019.
- Okumura H, Nakanishi A, Toyama S, Yamanoue M, Yamada K, Ukai A, Hashita T, Iwao T, Miyamoto T, Tagawa YI, Hirabayashi M, Miyoshi I, Matsunaga T.
Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation.
Xenotransplantation., 26;e12468:2019.
- Hori E, Kikuchi C, Imaeda K, Okayama N, Suzuki T, Matsunaga T.
Effect of Statins on Glycemic Status and Plasma Adiponectin Concentrations in Patients with Type 2 Diabetes Mellitus and Hypercholesterolemia
Yakugaku Zasshi., 139(5);807–815:2019.
- Sakai Y, Okumura H, Iwao T, Watashi K, Ito K, Matsunaga T.
Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration.
Toxicol In Vitro, 61;104619:2019.
- Sakai Y, Iwao T, Susukida T, Nukaga T, Takemura A, Sekine S, Ito K, Matsunaga T.
In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome.
Drug Metab Pharmacokinet, 34;264–271:2019.
- Koeda A, Iwao T, Nakanishi A, Mizuno S, Yamashita M, Sakai Y, Nakamura K, Matsunaga T.
Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes.
Drug Metab Pharmacokinet, 34;253–263:2019.
総説・著書・総合論文
- Iwao T, Matsunaga T.
Intestinal cells differentiated from human induced pluripotent stem cells for use in drug development studies.
Translat Regulat Sci, 1, 24–30, 2019.
- 岩尾岳洋，松永民秀．
薬物動態研究への応用を目指したiPS細胞由来肝･腸管上皮細胞の作製．
日本薬理学雑誌, 154 (2), 72–77, 2019.
- 岩尾岳洋，松永民秀．
Body-on-a chipと薬物動態：小腸と肝臓のデバイスを中心として．培養技術の新展開：マイクロ流体デバイスからbody-on-a-chipまで．
ファルマシア, 55 (5), 414–418, 2019.
招待講演
- 岩尾岳洋.
「創薬研究での利用に向けた小腸–肝臓連結デバイスの開発」
第46回日本毒性学会学術大会, 2019年6月26–28日（徳島）.
- 坡下真大.
「BBBモデルを目指したiPS細胞由来脳毛細血管内皮細胞の開発と課題」
実験動物代替法学会 第32回大会, 2019年11月20日-22日（つくば）
学会発表
ポスター発表（国際学会）
- Aoki H, Yamashita M, Hashita T, Iwao T, Matsunaga T.
Differentiation of human iPS cell-derived endothelial progenitor cells into brain microvascular endothelial cells.
EUROTOX 2019, Sep. 8-11 (2019), (Helsinki, Finland)
- Yamashita M, Aoki H, Hashita T, Iwao T, Matsunaga T.
Differentiation and freeze, thawing of human iPS cell-derived brain microvascular endothelial cells. EUROTOX 2019, Sep. 8-11 (2019), (Helsinki, Finland)
- Nakanishi A, Toyama S, Hashita T, Iwao T, Matsunaga T.
Evaluating the usefulness of human iPS cell-derived intestinal organoids for treatment of inflammatory bowel diseases.
The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics (JKPW 2019), Jul. 10-11 (2019), (Tokyo, Japan)
- Toyama S, Nakanishi A, Hashita T, Iwao T, Matsunaga T.
Therapeutic effects of transplant of human-induced pluripotent stem cell-derived intestinal stem cells in inflamatory bowel disease model mice.
The 10th meeting of Asian Cellular Therapy Organization. Nov. 7-9th (2019), (Sapporo, Japan)
ポスター発表（国内学会）
- 中山瑞希, 青木啓将, 坡下真大, 岩尾岳洋, 松永民秀.
iPS-sac由来血管内皮細胞前駆細胞の作出.
第46回日本毒性学会学術年会
賞
- 中山瑞希, 青木啓将, 坡下真大, 岩尾岳洋, 松永民秀:『iPS-sac由来血管内皮細胞前駆細胞の作出』
第46回日本毒性学会学術年会学生ポスター発表賞（2019）
- Toyama S, Nakanishi A, Hashita T, Iwao T, Matsunaga T.
Therapeutic effects of transplant of human-induced pluripotent stem cell-derived intestinal stem cells in inflamatory bowel disease model mice.
Best Abstract Award.
The 10th meeting of Asian Cellular Therapy Organization. Nov. 7-9th (2019), (Sapporo, Japan)
- YAMASHITA Misaki,
Compounds X promote the differentiation of human induced pluripotent stem cell-derived brain maicrovascular endothelial cells.
Best Poster Award.
NCU Contact Paints in Asia Symposium 2019.
